# A Rare Synchronous Existence of Warthin's Tumour and Oral Cancer: A systematic review

## TL;DR

This paper reviews rare cases where Warthin's tumour and oral cancer occur together, highlighting the importance of accurate diagnosis to avoid mismanagement.

## Contribution

The study systematically reviews and analyzes the rare synchronous occurrence of Warthin's tumour and oral squamous cell carcinoma.

## Key findings

- 13 papers with 17 cases of synchronous Warthin's tumour and oral cancer were identified.
- Over 50% of cases had a history of tobacco use, and many involved cervical lymph nodes.
- No recurrence was reported in the follow-up of these cases.

## Abstract

Oral squamous cell carcinoma (OSCC) is a common malignancy, while Warthin's tumour (WT) is a benign salivary gland neoplasm, typically found in the parotid gland but rarely involving extra-parotid tissues. The synchronous occurrence of OSCC and extra-parotid WT is particularly unusual. Accurate identification of these pathologies is crucial, as their rare presentation can resemble metastasis in lymph nodes. This review systematically searched for case reports and series of synchronous WT and OSCC, including 13 papers having 17 cases. The quality of these cases was assessed using CARE guidelines. The findings described WT's histological features and location in patients with OSCC, with many cases involving cervical lymph nodes. Over 50% of the cases had a history of tobacco use. Follow-up showed no recurrence in the reported cases. Awareness of the synchronous occurrence of WT and OSCC can prevent overtreatment and misdiagnosis, improving patient management.