Complete and draft genome sequences of clinical Mycobacterium tuberculosis isolates from the Philippines
Saul M. Rojas, Ma. Angelica A. Tujan, Angela Kae C. Valencia, Jessel Babe G. Capin, Timothy John R. Dizon, Ma. Cecilia G. Ama, Ramon P. Basilio, Dodge R. Lim, Lorenzo T. Reyes, Jody Phelan, Susana Campino, Taane G. Clark, Mari Rose A. De Los Reyes
TL;DR
This study provides genome sequences of 71 tuberculosis bacteria samples from the Philippines to better understand their diversity and drug resistance.
Contribution
The study presents complete and draft genomes of M. tuberculosis isolates using hybrid sequencing techniques.
Findings
Six complete genomes were assembled using hybrid sequencing.
The genomes reveal insights into M. tuberculosis diversity and drug resistance.
The data can support more effective targeted treatment strategies.
Abstract
This study reports the complete and draft genomes of 71 Mycobacterium tuberculosis isolates from the Philippines. Hybrid assembly using Illumina and Nanopore sequencing produced six complete genomes, while others had 2–422 contigs. These data enhance understanding of M. tuberculosis diversity and drug resistance, supporting targeted treatment strategies.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsMycobacterium research and diagnosis · Tuberculosis Research and Epidemiology · Bacteriophages and microbial interactions