# Draft genomes of 12 Ralstonia mannitolilytica isolates recovered from hospitalized patients and contaminated cosmetic water sprays

**Authors:** Trestan Pillonel, Dominique Blanc, Damien Jacot, Florian Mauffrey, Estelle Ben Salah-Moulin, Laurence Senn, Gilbert Greub, Claire Bertelli

PMC · DOI: 10.1128/mra.00300-25 · 2025-06-20

## TL;DR

This study sequenced 12 Ralstonia mannitolilytica genomes from patients and water sprays, showing the bacteria likely came from contaminated cosmetics.

## Contribution

The study provides draft genomes linking Ralstonia isolates from patients to contaminated cosmetic water sprays.

## Key findings

- Draft genomes of 12 Ralstonia isolates showed fewer than 10 SNPs.
- Genomic comparison indicated water sprays were the contamination source for patient infections.

## Abstract

Ralstonia mannitolilytica, an opportunistic pathogen commonly present in water, was identified in three hospitalized patients over a short period of time. The comparison of draft genomes of 12 isolates from patients and water sprays showed fewer than 10 single-nucleotide polymorphisms, indicating that water sprays were the contamination source.

## Linked entities

- **Species:** Ralstonia mannitolilytica (taxon 105219)

## Full-text entities

- **Species:** Ralstonia mannitolilytica (species) [taxon 105219], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12243527/full.md

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Source: https://tomesphere.com/paper/PMC12243527