# Draft genome of a vancomycin-resistant Enterococcus faecium recovered from a bloodstream infection

**Authors:** Ying Zeng, Donglai Dai, Yu Feng

PMC · DOI: 10.1128/mra.00518-25 · 2025-06-12

## TL;DR

Scientists sequenced the genome of a vancomycin-resistant Enterococcus faecium from a bloodstream infection patient.

## Contribution

The study provides a draft genome sequence of a vancomycin-resistant E. faecium strain with sequence type 80 and the vanA operon.

## Key findings

- The genome assembly consists of 243 contigs totaling 2,915,356 bp.
- The strain carries the vanA-type operon, associated with vancomycin resistance.
- The GC content of the genome is 37.66%.

## Abstract

We report the draft genome sequence of a vancomycin-resistant Enterococcus faecium, isolated from a patient with bloodstream infection. The strain was classified as sequence type 80 and carries the vanA-type operon. The final assembled genome assembly comprises 243 contigs totaling 2,915,356 bp, with a GC content of 37.66%.

## Linked entities

- **Chemicals:** vancomycin (PubChem CID 14969)
- **Species:** Enterococcus faecium (taxon 1352)

## Full-text entities

- **Genes:** vanA [NCBI Gene 13874695]
- **Diseases:** bloodstream infection (MESH:D018805)
- **Chemicals:** vancomycin (MESH:D014640)
- **Species:** Homo sapiens (human, species) [taxon 9606], Enterococcus faecium (species) [taxon 1352]

---
Source: https://tomesphere.com/paper/PMC12243480