# Cappable-seq RNA-sequencing data sets for comparative studying of Salmonella enterica adaptation to Acanthamoeba castellanii intracellular environment, oxidative stress, and starvation

**Authors:** Alexander Balkin, Andrey Plotnikov, Tatiana Konnova, Natalia Gogoleva, Elena Shagimardanova, Yuri Gogolev

PMC · DOI: 10.1128/mra.01129-24 · 2025-05-28

## TL;DR

This paper provides RNA sequencing data to study how Salmonella adapts to stress and intracellular environments.

## Contribution

The study introduces new Cappable-seq data sets for Salmonella under stress and intracellular conditions.

## Key findings

- Transcriptomic data was collected for Salmonella under starvation and hydrogen peroxide treatment.
- RNA sequencing was performed at specific time points after Acanthamoeba castellanii uptake.
- The data enables comparative analysis of Salmonella adaptation mechanisms.

## Abstract

Salmonella is a foodborne pathogen that can survive various stresses and replicate inside protist cells. Here, we present high-resolution Cappable-seq transcriptomic data for Salmonella enterica 14028S under starvation and hydrogen peroxide treatment, as well as 8 and 15 h after Acanthamoeba castellanii uptake.

## Linked entities

- **Chemicals:** hydrogen peroxide (PubChem CID 784)
- **Species:** Acanthamoeba castellanii (taxon 5755)

## Full-text entities

- **Chemicals:** hydrogen peroxide (MESH:D006861)
- **Species:** Salmonella enterica (species) [taxon 28901], Acanthamoeba castellanii (species) [taxon 5755]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12243465/full.md

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Source: https://tomesphere.com/paper/PMC12243465