# Jugular Vein Intracardiac Echocardiography-Guided Percutaneous Transluminal Septal Myocardial Ablation: A Novel Approach in 4 Cases

**Authors:** Hiroto Yagasaki, Keitaro Watanabe, Takeki Suzuki, Makoto Iwama, Shinichiro Tanaka, Toshiyuki Noda

PMC · DOI: 10.1016/j.jaccas.2025.103307 · 2025-03-12

## TL;DR

A new method for heart ablation using echocardiography through the jugular vein is described in four patients with heart disease.

## Contribution

A novel approach using jugular vein intracardiac echocardiography for septal myocardial ablation is introduced.

## Key findings

- The technique involves ICE-guided ablation through the right internal jugular vein.
- Real-time monitoring of ethanol injection and gradient reduction was achieved.
- The procedure showed potential for treating hypertrophic obstructive cardiomyopathy.

## Abstract

This study sought to describe a novel technique for percutaneous transluminal septal myocardial ablation using intracardiac echocardiography (ICE) through the right internal jugular vein (JV) in patients with hypertrophic obstructive cardiomyopathy.

Prepare the equipment and establish vascular access, insert the JV ICE catheter using a sterile sleeve, perform initial screening with JV ICE to obtain key cardiac views, identify target septal branch using coronary angiography and JV ICE, monitor contrast injection and ethanol administration in real time with JV ICE, continuously assess for immediate complications, and evaluate postprocedure gradient reduction and ablation efficacy.

Risks include vascular complications, arrhythmias, cardiac tamponade, embolism, and infections. JV ICE requires specific skills, presenting a learning curve. Mitigation strategies involve ultrasound-guided access, careful catheter manipulation, strict asepsis, comprehensive training, optimized settings, and continuous monitoring.

## Full-text entities

- **Diseases:** vascular complications (MESH:D003925), arrhythmias (MESH:D001145), hypertrophic obstructive cardiomyopathy (MESH:D002312), infections (MESH:D007239), cardiac tamponade (MESH:D002305), embolism (MESH:D004617)
- **Chemicals:** ethanol (MESH:D000431)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12243039/full.md

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Source: https://tomesphere.com/paper/PMC12243039