# E-cigarette flavor and device preferences among US pregnant women who smoke: A latent class analysis

**Authors:** Emily A. Doherty, Kayleigh A. Gregory, Yu Lu, Page D. Dobbs

PMC · DOI: 10.18332/tpc/204745 · 2025-07-10

## TL;DR

This study explores e-cigarette device and flavor preferences among pregnant women in the US who also smoke cigarettes.

## Contribution

The study identifies distinct subgroups of e-cigarette preferences among pregnant women using latent class analysis.

## Key findings

- Four classes of e-cigarette preferences were identified, with the majority preferring tobacco, mint, and sweet JUUL flavors.
- Pregnant women who smoked more cigarettes were more likely to use THC, all flavors, and JUUL devices.
- Findings suggest the need for targeted messaging campaigns considering device and flavor preferences.

## Abstract

Little is known about e-cigarette device and flavor preferences among pregnant women. The purpose of this study was to identify classes of e-cigarette use based on device and flavor preferences among pregnant women who report dual use of e-cigarettes and cigarettes.

A sample of pregnant women (n=118), aged 18–40 years, living in the US, with dual cigarette and e-cigarette use, completed a cross-sectional online survey. Participants reported e-cigarette characteristics including past 30-day e-cigarette device (cartridge-based, JUUL, tank, and disposable) and flavor use (tobacco, mint, spice, sweet, alcohol, combined), and use of e-cigarettes containing delta-9-tetrahydrocannabinol (THC) in pregnancy. We used latent class analysis to classify subgroups based on e-cigarette preferences in pregnancy and examined the association of sociodemographic variables and cigarette smoking frequency with class membership.

We found four distinct classes of e-cigarette preferences: Class 1) tobacco, mint, and sweet JUUL (50.4%); Class 2) THC, all flavors, and JUUL (28.1%); Class 3) THC, all flavors, and all device (12.4%); and Class 4) THC, tobacco, mint, sweet, and tank device (9.1%). Pregnant women who smoked ≥11 cigarettes per day, compared to those who smoked 1–10 per day, were 5.22 (95% CI: 1.85–14.70) and 5.55 times (95% CI: 1.49–20.61) as likely to use THC, all flavors, and JUUL and all devices, respectively, compared with those who used tobacco, mint, and sweet flavors with JUUL.

Pregnant dual users of cigarettes and e-cigarettes are a heterogenous group. Device and flavor differences should be considered when developing targeted messaging campaigns and prevention strategies.

## Linked entities

- **Chemicals:** delta-9-tetrahydrocannabinol (PubChem CID 2978), THC (PubChem CID 16078)

## Full-text entities

- **Chemicals:** JUUL (-), THC (MESH:D013759), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nicotiana tabacum (American tobacco, species) [taxon 4097]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12243033/full.md

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Source: https://tomesphere.com/paper/PMC12243033