# Structured Literature Review of the Impact of Using Cognitive-behavioural Therapy and Interpersonal Therapy On Depressive Symptoms in People Living With HIV/AIDS

**Authors:** June Kilonzo

PMC · DOI: 10.1192/bjo.2025.10161 · 2025-06-20

## TL;DR

This study reviews how cognitive-behavioral therapy and interpersonal therapy affect depression in people with HIV/AIDS, finding both helpful but with CBT showing slightly better results.

## Contribution

A structured literature review comparing the long-term effectiveness of CBT and IPT for depressive symptoms in people with HIV/AIDS.

## Key findings

- CBT showed significant long-term reduction in depressive symptoms over six months.
- IPT also had long-term effects, but with minimal symptom reduction compared to CBT.
- No significant difference in overall efficiency between the two therapies was observed.

## Abstract

Aims: A diagnosis of depression is three times more likely to occur in people living with HIV/AIDS. Management is imperative,as it not only ensures reduced depressive symptoms but also improves quality of life. Interpersonal psychotherapy (IPT) and cognitive-behavioural therapy (CBT) have been linked to reduced depressive symptoms. This paper will investigate to what degree both treatment options can help reduce depressive symptoms in people living with HIV/AIDS.

Methods: Randomized controlled trial articles from the Cardiff University repository, PsycARTICLES, PsycINFO, Cinahl, and PubMed databases were collected and dated not later than ten years from 2024. The participants were individuals with an HIV/AIDS diagnosis and depression as a comorbidity. They also had been exposed to either IPT or CBT psychotherapy. The articles were screened, and data from19 articles with 4805 participants were extracted.

Results: Findings showed that CBT reduced depressive symptoms, and its effects were visible in the long term, which involves more than six months. Similarly, IPT was found to have long-term effects, but the difference in the symptoms in IPT was minimal compared with CBT. No significant difference in the efficiency of either therapy was observed.

Conclusion: Both the psychotherapy modalities were found to have positive impact by reducing depressive symptoms. There is a need for more research into improving the psychotherapy intervention time and mode of delivery.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

---
Source: https://tomesphere.com/paper/PMC12241949