Scrotal wall metastasis of gastric adenocarcinoma: a rare case report and literature review

TL;DR

A rare case of gastric cancer spreading to the scrotal wall is reported, with successful surgical removal and no recurrence after three months.

Contribution

This paper presents a rare clinical case of gastric adenocarcinoma metastasis to the scrotal wall and confirms the diagnosis using immunohistochemical markers.

Findings

Scrotal wall metastasis of gastric adenocarcinoma was confirmed in a 60-year-old male patient.

Surgical excision of the scrotal lesion and follow-up showed no tumor recurrence after three months.

Immunohistochemical markers CK20, CK7, and CDX-2 confirmed the metastatic origin of the tumor.

Abstract

Metastasis of gastric adenocarcinoma typically involves the liver, peritoneum, and lymph nodes, whereas scrotal wall metastasis is extremely rare, with very few cases reported in the literature. We report a case of a 60-year-old male patient who presented with right-sided scrotal swelling. The patient had previously undergone total gastrectomy and multiple chemotherapy sessions for gastric adenocarcinoma. In June 2024, the scrotal wall metastasis of gastric adenocarcinoma was confirmed. The patient underwent excision of the right scrotal lesion, spermatic cord excision, and right epididymis and testis resection. Immunohistochemical markers, such as CK20, CK7, and CDX-2, were positive, which supported the diagnosis of metastatic gastric adenocarcinoma. Follow-up three months post-surgery showed no evidence of tumor recurrence.

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