# Sepsis Caused by Ewingella americana in an Immunocompromised Patient: A Case Report

**Authors:** Hala Jafarova Ayik, Cagla Eyupler, Gizem Yassa, Cagri Aksu, Nurcan Duman

PMC · DOI: 10.7759/cureus.85641 · 2025-06-09

## TL;DR

A cancer patient in Türkiye developed sepsis from a rare bacteria, Ewingella americana, during a blood transfusion and recovered after treatment.

## Contribution

First reported case of Ewingella americana infection in a cancer patient undergoing chemotherapy in Türkiye.

## Key findings

- Ewingella americana was identified as the causative agent through blood culture.
- The patient showed full recovery after treatment with ceftriaxone.
- No further bacterial growth was observed in subsequent blood cultures.

## Abstract

Human infections caused by Ewingella americana have been rarely described. We report a case of E. americana in a cancer patient undergoing chemotherapy, who developed sepsis during a red blood cell transfusion. This causative pathogen was identified through the patient’s blood culture. The patient was treated with ceftriaxone and showed complete clinical improvement, with no further growth of E. americana or other pathogenic isolates in subsequent blood cultures. To the best of our knowledge, this is the first reported case of E. americana infection in a cancer patient undergoing chemotherapy in Türkiye.

## Linked entities

- **Chemicals:** ceftriaxone (PubChem CID 5479530)
- **Diseases:** cancer (MONDO:0004992)
- **Species:** Ewingella americana (taxon 41202)

## Full-text entities

- **Diseases:** Sepsis (MESH:D018805), infection (MESH:D007239), cancer (MESH:D009369)
- **Chemicals:** ceftriaxone (MESH:D002443)
- **Species:** Homo sapiens (human, species) [taxon 9606], Ewingella americana (species) [taxon 41202], E. americana [taxon 399285]

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Source: https://tomesphere.com/paper/PMC12240595