# Pseudomyxoma Peritonei: Exploring an unusual clinical presentation – A case report

**Authors:** Mallak Al Naabi, Salim Al Busaidi, Amwaj Al Shahi, Maha Al Shaibi, Khalid Al Shamousi, Abdullah Al Alawi, Mohammed Al Hosni

PMC · DOI: 10.18295/2075-0528.2822 · 2025-05-02

## TL;DR

A 42-year-old woman with a rare condition called pseudomyxoma peritonei showed unusual symptoms and was successfully treated with surgery and chemotherapy.

## Contribution

This case report highlights an unusual clinical presentation of pseudomyxoma peritonei and the challenges in its diagnosis.

## Key findings

- The patient presented with chronic diarrhea and abdominal distension, which led to the discovery of pseudomyxoma peritonei.
- Diagnostic laparoscopy revealed a perforated appendicular mass and mucin ascites.
- Treatment with cytoreductive surgery and heated intraperitoneal chemotherapy resolved the patient's symptoms.

## Abstract

Pseudomyxoma peritonei (PMP) is a rare clinicopathological condition characterised by mucin-producing peritoneal and omental deposits with an estimated incidence of 1–2 cases per million per year. We report a 42-year-old female patient who presented to a tertiary care hospital in Muscat, Oman, in 2023 due to a 7-year history of chronic diarrhoea associated with progressive abdominal distension over the past 2 years. Her assessment was significant for ascites. No neoplastic lesions were found on the upper and lower gastrointestinal scopes. A diagnostic ascitic tapping revealed a free flow of gel-like thick, yellowish fluid. A diagnostic laparoscopy showed a perforated appendicular mass with diffuse peritoneal nodules and mucin ascites. Subsequently, the patient underwent cytoreductive surgery with heated intraperitoneal chemotherapy. On follow-up, the patient's abdominal distension and diarrhoea had resolved. This case reports an unusual presentation of a very rare disorder and highlights the challenge of diagnosing PMP.

## Linked entities

- **Diseases:** pseudomyxoma peritonei (MONDO:0017048)

## Full-text entities

- **Genes:** mucin [NCBI Gene 100508689]
- **Diseases:** mass (MESH:C536030), diarrhoea (MESH:D003967), abdominal distension (MESH:D000007), ascites (MESH:D001201), PMP (MESH:D011553)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12240162/full.md

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Source: https://tomesphere.com/paper/PMC12240162