# Overcoming Barriers in the Surgical Management of Osteogenesis Imperfecta: Insights From a 13-Year Retrospective Cohort

**Authors:** Hamza Bensaghir, Sarah Hosni, Chaimae Ben Driss, Loubna Aqqaoui, Houda Oubejja, Sidi Zouhair Fellous El Alami, Fouad Ettayebi, Tarik El Madhi

PMC · DOI: 10.7759/cureus.85610 · Cureus · 2025-06-09

## TL;DR

This study shows that telescopic nailing is more effective than traditional methods for treating bone fractures in patients with osteogenesis imperfecta.

## Contribution

The study provides evidence that telescopic nailing reduces fractures and deformities in osteogenesis imperfecta patients compared to traditional rodding.

## Key findings

- Telescopic nailing significantly reduced fracture frequency in OI patients.
- Telescopic nailing decreased the need for reintervention compared to traditional rodding.
- Telescopic nails allowed normal growth while preventing deformities.

## Abstract

Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility and reduced bone mass. This retrospective study analyzed 42 cases of OI treated at the pediatric traumatology and orthopedics department over a 13-year period. The study aimed to examine the clinical and radiological aspects associated with osteosynthesis, particularly telescopic nailing, in these patients. Patients were grouped by treatment type, and outcomes, including fracture frequency, deformity recurrence, need for reintervention, and functional status, were compared. Results showed that telescopic nailing significantly reduced the number of fractures, deformities, and reinterventions compared to traditional rodding techniques. The study concludes that telescopic nails are beneficial in preventing deformities and fractures while allowing normal growth, making them the preferred method for managing patients with OI.

## Linked entities

- **Diseases:** Osteogenesis Imperfecta (MONDO:0019019)

## Full-text entities

- **Diseases:** bone fragility (MESH:C536063), fracture (MESH:D050723), genetic disorder (MESH:D030342), OI (MESH:D010013), deformities (MESH:D009140), reduced bone mass (MESH:D001847)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12239692/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12239692/full.md

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Source: https://tomesphere.com/paper/PMC12239692