# Cardiac calcified amorphous tumor in the right atrium: a rare cardiac neoplasm

**Authors:** Wentao Fu, Kun Liu, Yan Zhang, Jing Wang, Wan Cai, Yaoyao Wu, Hao Chi, Wen Ge

PMC · DOI: 10.1186/s13019-025-03501-y · Journal of Cardiothoracic Surgery · 2025-07-09

## TL;DR

A rare cardiac calcified amorphous tumor was found in a 46-year-old man's right atrium and successfully treated surgically.

## Contribution

This case report adds to the limited literature on cardiac calcified amorphous tumors in the right atrium.

## Key findings

- A 13.2 × 11.8 mm calcified amorphous tumor was identified in the right atrium via echocardiography.
- Histopathology confirmed the diagnosis, showing calcified areas and minimal inflammatory cells.
- Surgical resection is recommended, though anticoagulation and surveillance are alternatives in high-risk cases.

## Abstract

Cardiac calcified amorphous tumors (CATs) represent rare, nonneoplastic intraluminal heart masses, with limited case reports in existing literature. Asymptomatic cases localized in the right atrium are particularly unusual.

An asymptomatic 46-year-old male was discovered to have a cardiac mass upon echocardiograph. Echocardiography revealed a 13.2 × 11.8 mm pedunculated mass in the right atrium, attached to the interatrial septum. Then we performed surgical treatment. Histopathology revealed some myocardial tissue, a powdery stained, calcified amorphous area, and a few localized lymphocytes and red blood cells. The final diagnosis confirmed a cardiac CAT.

CATs, rarely occurring endocardium-based pseudotumors, comprise calcium nodules and amorphous fibrin material. Typically presenting as a calcified pedunculated mass, they may arise in any heart chamber, with a significant propensity for distal embolism. Differentiating CATs from calcified atrial myxomas, calcified thrombi, or other cardiac tumors is challenging. Histopathology remains a critical diagnostic cornerstone. Although complete surgical resection is the recommended treatment, anticoagulation and ongoing surveillance may serve as viable alternatives when primary treatment, surgical resection, is deemed excessively hazardous.

## Full-text entities

- **Diseases:** cardiac neoplasm (MESH:D006338), calcified atrial myxomas (MESH:C538262), tumor (MESH:D009369), heart masses (MESH:C536030), CATs (MESH:C537961), distal embolism (MESH:D004617), cardiac CAT (MESH:D006331), calcified thrombi (MESH:D018333)
- **Chemicals:** calcium (MESH:D002118)

## Full text

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12239440/full.md

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Source: https://tomesphere.com/paper/PMC12239440