# An interdisciplinary approach for the management of periapical lesion using regenerative approach: a case report

**Authors:** Priyanka Jaiswal, Sakshi Vishal Kotecha, Shweta Bhagat, Shweta Sedani, Akash Thakare

PMC · DOI: 10.1186/s13256-025-05380-2 · Journal of Medical Case Reports · 2025-07-09

## TL;DR

This case report discusses a regenerative treatment approach for a complex dental lesion in a 32-year-old woman.

## Contribution

The paper highlights a multidisciplinary treatment strategy for challenging periapical lesions.

## Key findings

- A 32-year-old patient presented with a periapical lesion requiring regenerative treatment.
- Histopathological analysis confirmed a dental cyst in the upper right jaw region.
- The case emphasizes the need for a multidisciplinary approach in managing complex lesions.

## Abstract

Periapical lesions are common sequelae of endodontic infections, often presenting as chronic apical periodontitis. These lesions result from the microbial invasion of the root canal system, leading to inflammation and subsequent bone resorption. While conventional root canal therapy is the primary treatment modality, it occasionally fails to resolve periapical pathology. In such cases, surgical intervention becomes necessary.

This report presents the case of a 32-year-old female of Indian ethnicity with chief complaints of pain and pus discharge in the upper right front area in the past 2 months. Radiographic findings were evident, depicting periapical radiolucency. Upon debriding the lesion, it was observed to be creamish with irregular shape and size and, hence, it was sent for histopathological analysis. It was inferred to be a dental cyst associated with the right upper front region of the jaw.

This case report pinpoints the importance of considering the diagnosis of periapical lesions. It also adds to the point of treatment plan that can be followed as a multidisciplinary approach to challenging periapical lesions.

## Linked entities

- **Diseases:** chronic apical periodontitis (MONDO:0001251)

## Full-text entities

- **Diseases:** apical periodontitis (MESH:D010485), inflammation (MESH:D007249), bone resorption (MESH:D001862), Periapical lesions (MESH:D010483), endodontic infections (MESH:D011671), pain (MESH:D010146), dental cyst (MESH:D003560)

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12239431/full.md

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Source: https://tomesphere.com/paper/PMC12239431