# Lower Cervical Chordomas: A Case Report and Differential Diagnosis

**Authors:** Yosita Muenkaew, Artit Jinawath, Wichit Cheewaruangroj

PMC · DOI: 10.1002/cnr2.70270 · Cancer Reports · 2025-07-09

## TL;DR

This paper reports a rare case of a chordoma in the lower cervical spine, emphasizing the challenges in diagnosis and treatment.

## Contribution

The novelty lies in presenting a rare clinical case of lower cervical chordoma with detailed diagnostic and treatment insights.

## Key findings

- Chordomas in the lower cervical region are rare and may present as a neck mass.
- Accurate diagnosis requires imaging and histological confirmation via biopsy and immunohistochemistry.
- Surgical resection is the primary treatment, with adjunct therapies for residual or recurrent disease.

## Abstract

Chordomas are rare tumors that arise from notochord remnants and are typically located in the axial skeleton. Chordomas arising in the lower cervical spine are rare.

We report a case of a 79‐year‐old man who presented with a lump on the left side of his neck, indicating an unusual presentation of a chordoma in the lower cervical region. This report describes the clinical, radiological, and histological results of this patient who sought medical attention for a left‐sided neck mass. Additional diagnostic tests, including immunohistochemistry and biopsy, confirmed the existence of a chordoma affecting the lower cervical region.

The precision of a diagnosis of cervical chordoma hinges on imaging study results and confirmation provided by histological examination, typically through biopsy and immunohistochemistry. The primary treatment for cervical chordoma is the surgical resection. Adjunctive therapies, such as radiation therapy and, in some cases, chemotherapy, may be used to manage residual disease or recurrent tumors.

This case emphasizes the rarity of lower cervical chordomas, which present as a neck mass and are a diagnostic dilemma. Total excision is complex and relies on combining multiple disciplines including imaging, immunohistochemistry, and adjunct radiation therapy. Long‐term follow‐up and early detection are key to better outcomes and reduced recurrence.

5.

## Linked entities

- **Diseases:** chordoma (MONDO:0008978)

## Full-text entities

- **Diseases:** Cervical Chordomas (MESH:D002817), neck mass (MESH:D006258), tumors (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12238892/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12238892/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12238892/full.md

---
Source: https://tomesphere.com/paper/PMC12238892