# Home‐based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti‐BP180‐NC16a antibody

## TL;DR

An elderly man with bullous pemphigoid was successfully treated at home, with antibody levels changing as the disease progressed.

## Contribution

This case demonstrates the feasibility of home-based care for severe bullous pemphigoid and the importance of reevaluating antibody status.

## Key findings

- The patient's anti-BP180-NC16a antibody turned positive as disease severity increased.
- Home-based multidisciplinary management was effective for a severe case of bullous pemphigoid.
- Delayed seropositive conversion of anti-BP180-NC16a antibody was observed in a bedridden patient.

## Abstract

We report the case of an 82‐year‐old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home‐based care. Anti‐BP180‐NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home‐visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti‐BP180‐NC16a antibody levels and the feasibility of home‐based care for severe bullous pemphigoid in bedridden patients.

We present the case of an elderly male with bullous pemphigoid, initially negative for the anti‐BP180‐NC16a antibody, which later became positive as disease activity progressed. The patient was successfully managed at home through multidisciplinary collaboration, including a general practitioner, dermatologist, nurses, and pharmacists.