# Large Left Atrial Myxoma Presenting as Functional Mitral Stenosis: A Multimodal Imaging Case Report

**Authors:** Esperance M Madera, Elda Mullaj, Anish Munagala, Gustavo Espinoza Mercado, Neeta Reddy, Induja Rajendran, Daniela Filip Kovacs, Anura Manandhar, Prakash Oli

PMC · DOI: 10.7759/cureus.87401 · Cureus · 2025-07-06

## TL;DR

A 71-year-old woman with a large left atrial myxoma experienced symptoms of heart obstruction, which was diagnosed and surgically removed.

## Contribution

This case report presents a rare instance of a myxoma causing functional mitral stenosis.

## Key findings

- Transthoracic echocardiography identified a 6.4×3.9 cm left atrial myxoma.
- The tumor caused functional severe mitral stenosis with a 15 mmHg gradient.
- Surgical resection confirmed the tumor size as 7.1×7×4 cm.

## Abstract

A 71-year-old woman with no prior cardiac history presented to the cardiology clinic following referral from her primary care physician for evaluation of progressive dyspnea, fatigue, and palpitations over a six-month period. Transthoracic echocardiography revealed a large, mobile mass attached to the interatrial septum measuring 6.4×3.9 cm, consistent with a left atrial myxoma. There was evidence of left ventricular inflow obstruction, with a mean mitral valve gradient of 15 mmHg. Further assessment determined that the mass was causing functional severe mitral stenosis, resulting in impaired left ventricular filling. A transesophageal echocardiogram confirmed the presence of the mass. The patient subsequently underwent surgical resection of the tumor via cardiopulmonary bypass. Intraoperative findings confirmed a left atrial myxoma measuring 7.1×7×4 cm. This case highlights a rare presentation of a rapidly enlarging atrial myxoma leading to functional mitral stenosis.

## Linked entities

- **Diseases:** mitral stenosis (MONDO:0005852)

## Full-text entities

- **Diseases:** impaired left ventricular (MESH:D018487), palpitations (MESH:D006331), tumor (MESH:D009369), Left Atrial Myxoma (MESH:C538262), fatigue (MESH:D005221), left ventricular inflow obstruction (MESH:D000092242), dyspnea (MESH:D004417), Mitral Stenosis (MESH:D008946)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12237215/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12237215/full.md

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Source: https://tomesphere.com/paper/PMC12237215