# Non-occlusive Mesenteric Ischemia Following Transcatheter Aortic Valve Replacement: A Case Report

**Authors:** George C Michalopoulos, Viktoriya Bikeyeva, Giovanni Paolella, Joseph Adams, Andrii Labchuk, Adib Chaus

PMC · DOI: 10.7759/cureus.87468 · Cureus · 2025-07-07

## TL;DR

A 79-year-old woman with a history of aortic aneurysm repair developed severe intestinal damage after a heart valve procedure, highlighting the risk of a rare complication.

## Contribution

The paper proposes a new mechanism linking TAVR to NOMI through reduced cardiac output during valve deployment.

## Key findings

- NOMI after TAVR can lead to extensive bowel necrosis and death.
- Patients with prior endovascular interventions are at higher risk for post-TAVR NOMI.
- Rapid pacing during TAVR may reduce splanchnic blood flow in those with pre-existing mesenteric disease.

## Abstract

Non-occlusive mesenteric ischemia (NOMI) is a rare complication after transcatheter aortic valve replacement (TAVR), with a poorly understood pathogenesis. We present the case of a 79-year-old female with a history of surgically repaired abdominal aortic aneurysm (AAA) and stable thoracic aortic aneurysm (TAA) who developed NOMI after TAVR, resulting in extensive bowel necrosis and patient mortality. Our case highlights the special attention that must be paid to patients with a history of endovascular interventions prior to TAVR due to the risk of postprocedural NOMI. We propose that NOMI after TAVR occurs from the reduction in cardiac output due to rapid pacing during valve deployment, resulting in worsening splanchnic hypoperfusion in patients with existing mesenteric vascular disease.

## Linked entities

- **Diseases:** abdominal aortic aneurysm (MONDO:0005350), thoracic aortic aneurysm (MONDO:0005396)

## Full-text entities

- **Diseases:** NOMI (MESH:D065666)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12237081/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12237081/full.md

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Source: https://tomesphere.com/paper/PMC12237081