# Formulation, evaluation and antimicrobial effect of herbal disinfectants

## TL;DR

Researchers developed and tested herbal disinfectants from local plants, finding they effectively combat hospital microbes.

## Contribution

The study introduces new herbal disinfectant formulations with strong antimicrobial potential against hospital pathogens.

## Key findings

- Acacia nilotica disinfectant showed 35mm higher inhibition against Citrobacter koseri than standard antibiotics.
- FTIR analysis confirmed bioactive compounds in Acacia nilotica, Moringa oleifera, and Senna alata formulations.
- Herbal disinfectants show promise in combating antimicrobial resistance in healthcare settings.

## Abstract

The cost-effective herbal disinfectant formulations from indigenously available plants with their potential antimicrobial activity
against hospital-derived microbial flora are of interest. Hence, a total of six herbal disinfectant formulations were prepared with
indigenously available plants and tested for the antimicrobial activity using a standard protocol. The results show that
Citrobacter koseri isolated from the Ophthalmology ward showed the highest sensitivity to Acacia
nilotica herbal disinfectant and the inhibition zone identified was 35mm higher than standard tested antibiotics. Chemical
composition analysis of Acacia nilotica, Moringa oleifera, and Senna alata herbal
formulations using qualitative and FTIR methods showed the presence of various bioactive compounds contributing to their antimicrobial
activity. Thus, the promise for advancing infection control practices in addressing the challenges of antimicrobial resistance in
healthcare settings is evident.