# Hypertensive disorder prediction among first-trimester antenatal patients using Gestosis score

**Authors:** Aashamika P Kundargi, Jagrati K Naagar, Roopali Jain, Nitu Mishra, Priyanka Tiwari

PMC · DOI: 10.6026/973206300210618 · Bioinformation · 2025-04-30

## TL;DR

A new scoring system called Gestosis Score accurately predicts pre-eclampsia in early pregnancy using simple maternal data.

## Contribution

The Gestosis Score is a novel, cost-effective tool for early prediction of hypertensive disorders in pregnancy.

## Key findings

- A Gestosis Score of ≥3 predicted pre-eclampsia with 84.64% sensitivity and 96.04% specificity.
- 17.23% of participants developed pre-eclampsia, showing a strong correlation with higher scores.
- The score is practical for use in resource-limited settings to identify high-risk pregnancies early.

## Abstract

The hypertensive disorders of pregnancy Gestosis Score is a cost-effective tool designed to predict hypertensive disorders of
pregnancy (HDP), including pre-eclampsia, using maternal history, clinical parameters and laboratory data. Hence, a study of 100
first-trimester antenatal patients found that a Gestosis Score of ≥3 had a sensitivity of 84.64%, specificity of 96.04% and
diagnostic accuracy of 93.00% for predicting pre-eclampsia. Pre-eclampsia developed in 17.23% of participants, with a significant
correlation between higher Gestosis Scores and increased risk (p < 0.05). Primigravida women (78%) and younger age groups (21-25
years, 49%) were predominant in the study population. The hypertensive disorders of pregnancy Gestosis Score are a reliable and
practical screening tool, particularly beneficial in resource-limited settings for early identification of high-risk pregnancies and
timely intervention to improve maternal and fetal outcomes.

## Linked entities

- **Diseases:** pre-eclampsia (MONDO:0005081)

## Full-text entities

- **Diseases:** Gestosis (MESH:D011225), HDP (MESH:D046110), Hypertensive disorder (MESH:D006973)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12236535/full.md

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Source: https://tomesphere.com/paper/PMC12236535