# Risk group-4 virus emergent threats

**Authors:** Paul Shapshak, Seetharaman Balaji, Charurut Somboonewit, John T. Sinnott, Francesco Chiappelli

PMC · DOI: 10.6026/973206300210721 · Bioinformation · 2025-04-30

## TL;DR

This paper discusses ongoing threats from Filovirus outbreaks in Africa and emphasizes the need for global strategies to prevent future pandemics.

## Contribution

The paper highlights the persistent risks of Filoviruses and advocates for expanded global pandemic preparedness.

## Key findings

- Filovirus outbreaks from 2021-2025 in Africa had high case fatality ratios.
- Epidemics continued despite being declared terminated due to virus pathogenicity and transmissibility.
- Collaborative global strategies are needed to mitigate future outbreaks.

## Abstract

Several Filovirus outbreaks occurred during 2021-2025 in Africa. The case fatality ratios (CFRs) were elevated as expected for these
viruses. After outbreaks were termed terminated, nonetheless, due to virus pathogenicity and transmissibility, epidemics continued
unabated. To mitigate future outbreaks and bolster pandemic preparedness, collaborative global strategies should continue and expand.

## Full-text entities

- **Species:** Filoviridae (family) [taxon 11266]

## Full text

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12236526/full.md

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Source: https://tomesphere.com/paper/PMC12236526