# DiscMycoVir: a user-friendly platform for discovering mycoviruses in fungal transcriptomes

**Authors:** Agorakis Bompotas, Nikitas-Rigas Kalogeropoulos, Maria Giachali, Ioly Kotta-Loizou, Christos Makris

PMC · DOI: 10.1186/s12859-025-06196-z · BMC Bioinformatics · 2025-07-07

## TL;DR

DiscMycoVir is a user-friendly platform for identifying mycoviruses in fungal RNA-seq data, making virus discovery accessible even to non-experts.

## Contribution

The novel contribution is a streamlined, accessible pipeline for mycovirus discovery in fungal transcriptomes, requiring no programming skills.

## Key findings

- DiscMycoVir successfully identified mycoviruses in RNA-seq data from Candida auris.
- The platform combines existing tools into a user-friendly interface for non-technical users.
- It is adaptable for virus detection in transcriptomes from other organisms.

## Abstract

The article presents DiscMycoVir, an elegant and user-friendly platform for discovering mycoviruses in fungal transcriptomes. DiscMycoVir is a pipeline of established tools for next-generation sequencing analysis and database searching, incorporated in an interface that facilitates accessibility even for users that have no programming skills and expertise. A comprehensive and detailed result report enhances user experience. DiscMycoVir can be accessed online for reviewing purposes at: https://discmycovir.imslab.gr:8000 and the source code is located at https://github.com/abompotas/DiscMycoVir. We recommend using the GitHub repository, as the online platform may lack the necessary resources to ensure uninterrupted service especially on large files.

We employed state-of-the-art technologies in the design and implementation phase of the platform. We present the application of the platform in screening RNA-seq data from the yeast Candida auris for mycoviruses, demonstrating its efficiency and simplicity in use.

DiscMycoVir serves as a user-friendly platform for identifying mycoviruses in RNA-seq data. Our tool was successfully implemented to discover mycoviruses in a C. auris isolate and could be adapted to detect viruses in transcriptomes from other organisms as well.

## Full-text entities

- **Species:** Candidozyma auris (species) [taxon 498019], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12235966/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12235966/full.md

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Source: https://tomesphere.com/paper/PMC12235966