# A Case Report of Good’s Syndrome Diagnosed After Thymomectomy

**Authors:** Muhammad Izzul Hazim Ahmad, Chee Yik Chang

PMC · DOI: 10.7759/cureus.85545 · Cureus · 2025-06-08

## TL;DR

A patient developed recurring infections after thymoma surgery, leading to a diagnosis of Good’s syndrome, a rare immune disorder.

## Contribution

This case report highlights the diagnostic importance of Good’s syndrome in thymoma patients with recurrent infections.

## Key findings

- The patient experienced multiple pneumonias and persistent diarrhea post-thymomectomy.
- Diagnosis of Good’s syndrome was confirmed due to hypogammaglobulinemia and B-cell deficiency.
- The case underscores the need for immune evaluation in thymoma patients with recurrent infections.

## Abstract

Good's syndrome is a rare immunodeficiency disorder associated with thymoma, characterized primarily by hypogammaglobulinemia and B-cell deficiency. Patients with Good’s syndrome exhibit compromised immunity, rendering them highly susceptible to recurrent infections. This report describes the case of a patient who developed multiple episodes of pneumonia and persistent diarrhea following thymomectomy for thymoma, ultimately leading to the diagnosis of Good's syndrome. The clinical course highlights the importance of considering this diagnosis in patients with thymoma who present with recurrent infections.

## Linked entities

- **Diseases:** pneumonia (MONDO:0005249), thymoma (MONDO:0006456)

## Full-text entities

- **Diseases:** infections (MESH:D007239), hypogammaglobulinemia (MESH:D000361), pneumonia (MESH:D011014), immunodeficiency disorder (MESH:D000081207), thymoma (MESH:D013945), Good's Syndrome (MESH:D005359), B-cell deficiency (MESH:D015448), diarrhea (MESH:D003967)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12235330/full.md

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Source: https://tomesphere.com/paper/PMC12235330