# Pure red-cell aplasia after radioactive iodine treatment in a patient with papillary thyroid cancer and follow up for two years: a case report

## TL;DR

A patient with papillary thyroid cancer developed pure red-cell aplasia after radioactive iodine treatment and recovered with medication over two years.

## Contribution

This is the first reported case linking radioactive iodine therapy to acquired pure red-cell aplasia.

## Key findings

- Radioactive iodine therapy was associated with the onset of pure red-cell aplasia in a thyroid cancer patient.
- The patient's condition normalized after two years of treatment with cyclosporine, stanozolol, and diammonium glycyrrhizinate.

## Abstract

Acquired pure red cell aplasia (PRCA) has attracted more and more attention in hematology. PRCA usually caused by infection, autoimmune diseases, thymic carcinoma, or drugs, has not been reported by radioactive iodine. Here we report a case of PRCA after radioactive iodine therapies (two times, 100 mCi and 130 mCi each) in a patient with papillary thyroid carcinoma and follow up for two years. she was treatment with cyclosporine (100mg twice per day), stanozolol (2mg three times per day) and diammonium glycyrrhizinate (150mg three times per day), returned to the normal range in 2024.