# Sublingual Dermoid Cyst Mimicking Ranula on Imaging: Surgical Treatment and Outcome in a Human Immunodeficiency Virus (HIV)-Positive Patient

**Authors:** Gulistan Bano, Dheeraj Kumar, Swaha Panda, Bhartendu Bharti, Pradosh Kumar Sarangi

PMC · DOI: 10.7759/cureus.85534 · Cureus · 2025-06-07

## TL;DR

A rare case of a sublingual dermoid cyst in an HIV-positive patient was successfully treated surgically after being misdiagnosed as a ranula on imaging.

## Contribution

This case highlights the importance of considering dermoid cysts in the differential diagnosis of sublingual swellings, even when imaging suggests otherwise.

## Key findings

- The patient's sublingual mass was confirmed as a dermoid cyst via histopathological analysis after imaging suggested ranula.
- Surgical excision via an extraoral approach successfully removed the cyst with no recurrence at three months.
- Imaging modalities like ultrasonography and CT may not always provide a definitive diagnosis for sublingual masses.

## Abstract

Dermoid cysts are rare congenital lesions that arise due to the entrapment of ectodermal and mesodermal elements during embryonic development. We report the case of a 21-year-old male with HIV who presented with a longstanding sublingual mass associated with difficulty in chewing and swallowing. Clinical examination revealed a firm, non-tender, and mobile sublingual mass, accompanied by concurrent submental swelling. Ultrasonography and computed tomography of the neck were suggestive of ranula. The patient underwent surgical excision through an extraoral submental approach under general anesthesia. The cyst was found to be attached to the mylohyoid muscle and was carefully dissected and removed in its entirety. Histopathological analysis confirmed a dermoid cyst, showing stratified squamous epithelium lined by keratin and sebaceous glands. The patient's postoperative recovery was smooth, with no recurrence noted at the three-month follow-up. Although rare, dermoid cysts of the oral cavity should be considered in the differential diagnosis of midline sublingual swellings. Imaging modalities, including ultrasonography and computed tomography (CT), are integral for preoperative assessment, although they may occasionally present challenges in achieving a definitive diagnosis. Complete surgical excision is the definitive treatment, with the decision to use either an intraoral or extraoral approach based on the size and location of the cyst and the risk of infection. Early detection and treatment are vital to avoid complications like airway obstruction and difficulty swallowing.

## Linked entities

- **Diseases:** ranula (MONDO:0001600)

## Full-text entities

- **Diseases:** Ranula (MESH:D011900), airway obstruction (MESH:D000402), cyst (MESH:D003560), congenital lesions (MESH:D009059), Dermoid Cyst (MESH:D003884), swelling (MESH:D004487), midline sublingual swellings (MESH:D013362), infection (MESH:D007239)
- **Species:** Human immunodeficiency virus (species) [taxon 12721], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12234258/full.md

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Source: https://tomesphere.com/paper/PMC12234258