# Cavernous Sinus Endodermal Cyst: A Report of a Rare Case

**Authors:** Shintaro Arai, Tohru Mizutani, Katusyoshi Shimizu, Kouzou Murakami, Yoichi Morofuji

PMC · DOI: 10.7759/cureus.85497 · 2025-06-07

## TL;DR

A rare case of a cavernous sinus endodermal cyst was successfully diagnosed and surgically removed in a 36-year-old man.

## Contribution

This report adds a rare clinical case of endodermal cyst in the cavernous sinus to the medical literature.

## Key findings

- The patient presented with trigeminal nerve pain and a cystic tumor in the cavernous sinus.
- Histological analysis confirmed the tumor as an endodermal cyst, not a schwannoma.
- The case highlights the importance of considering endodermal cysts in differential diagnoses of cavernous sinus tumors.

## Abstract

Endodermal cysts of the cavernous sinus are extremely rare. We report the case of a 36-year-old man who presented with spontaneous pain in the ophthalmic (V1) and maxillary (V2) divisions of the trigeminal nerve. Based on the preoperative imaging findings, a cystic trigeminal schwannoma was suspected. The tumor was removed via an extradural middle fossa transcavernous approach, and histological examination confirmed the diagnosis of an endodermal cyst. Endodermal cysts should be considered in the differential diagnosis of cavernous sinus tumors.

## Full-text entities

- **Diseases:** Endodermal Cyst (MESH:D018240), trigeminal schwannoma (MESH:D009442), cavernous sinus tumors (MESH:D020226), pain (MESH:D010146), tumor (MESH:D009369)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12230873/full.md

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Source: https://tomesphere.com/paper/PMC12230873