# A rare Wohlfahrtiimonas strain linked to human infection

**Authors:** Peiying Huang, Chao Yang, Meifang Lin, Guanghui Song, Ping-Hua Qu, Li Chen

PMC · DOI: 10.3389/fcimb.2025.1609676 · 2025-06-23

## TL;DR

A rare Wohlfahrtiimonas strain, not previously known to infect humans, is found to cause infection in a new case.

## Contribution

Identification of a new Wohlfahrtiimonas strain linked to human infection through genomic analysis.

## Key findings

- A new Wohlfahrtiimonas strain was identified in a human infection case.
- The strain is closely related to W. chitiniclastica but is an unclassified species.
- 16S rRNA and whole-genome sequencing confirmed the novelty of the strain.

## Abstract

Wohlfahrtiimonas is an infrequently encountered Gram-negative bacterium capable of infecting humans and, in severe instances, precipitating sepsis. Presently, three species within the Wohlfahrtiimonas genus have been identified, with Wohlfahrtiimonas chitiniclastica being the sole species implicated in human infections. To date, there has been only one documented case of human infection with W. chitiniclastica in China. In this study, we present an additional case of human infection with a Wohlfahrtiimonas species. Notably, through 16S rRNA gene sequencing and whole-genome sequencing, the strain was identified as an unclassified species closely related to W. chitiniclastica DSM 18708T.

## Linked entities

- **Species:** Wohlfahrtiimonas chitiniclastica (taxon 400946), Wohlfahrtiimonas (taxon 582472)

## Full-text entities

- **Diseases:** infection (MESH:D007239), sepsis (MESH:D018805)
- **Species:** Wohlfahrtiimonas (genus) [taxon 582472], Wohlfahrtiimonas chitiniclastica (species) [taxon 400946], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12229853/full.md

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Source: https://tomesphere.com/paper/PMC12229853