# Efficient sparse-view medical image classification for low radiation and rapid COVID-19 diagnosis

**Authors:** Seunghyun Gwak, Sooyoung Yang, Heawon Jeong, Junhu Park, Myungjoo Kang

PMC · DOI: 10.1007/s13534-025-00478-4 · 2025-05-22

## TL;DR

A new deep learning model called ProMAE can diagnose COVID-19 from sparse CT scans with high accuracy, reducing radiation exposure and enabling faster diagnosis.

## Contribution

ProMAE introduces a column-wise masking strategy for learning diagnostic features directly from sparse-view sinograms without reconstruction.

## Key findings

- ProMAE achieves over 95% diagnostic accuracy at all sparsity levels up to 99%.
- ProMAE outperforms ResNet, ConvNeXt, and conventional MAE models in high sparsity environments.
- The model enables accurate diagnosis with minimal radiation exposure, suitable for portable imaging systems.

## Abstract

This study proposes a deep learning-based diagnostic model called the Projection-wise Masked Autoencoder (ProMAE) for rapid and accurate COVID-19 diagnosis using sparse-view CT images. ProMAE employs a column-wise masking strategy during pre-training to effectively learn critical diagnostic features from sinograms, even under extremely sparse conditions. The trained ProMAE can directly classify sparse-view sinograms without requiring CT image reconstruction. Experiments on sparse-view data with 50%, 75%, 85%, 95%, and 99% sparsity show that ProMAE achieves a diagnostic accuracy of over 95% at all sparsity levels and, in particular, outperforms ResNet, ConvNeXt, and conventional MAE models in COVID-19 diagnosis in environments with 85% or higher sparsity. This capability is especially advantageous for the development of portable and flexible imaging systems during large-scale outbreaks such as COVID-19, as it ensures accurate diagnosis while minimizing radiation exposure, making it a vital tool in resource-limited and high-demand settings.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382)

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12229398/full.md

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Source: https://tomesphere.com/paper/PMC12229398