# Diagnostic Pitfalls in Peritoneal Carcinomatosis: A Case of Pseudomyxoma Peritonei

## TL;DR

This case study highlights the diagnostic challenges of pseudomyxoma peritonei and shows successful treatment with surgery and chemotherapy.

## Contribution

The paper emphasizes the importance of accurate pathological diagnosis for effective treatment of PMP.

## Key findings

- Initial misdiagnosis of PMP as primary peritoneal carcinoma was corrected through histopathological review.
- Aggressive treatment with CRS and HIPEC led to a 12-month disease-free outcome in the patient.
- Pathological assessment is critical for guiding appropriate management of PMP.

## Abstract

Pseudomyxoma peritonei (PMP) is a rare pathological condition posing significant diagnostic and management challenges. This article presents a clinical case of a 58-year-old female who was initially diagnosed with stage III primary peritoneal carcinoma. Following neoadjuvant chemotherapy, a diagnostic re-evaluation was performed with histopathological and immunohistochemical review of biopsy specimens, which led to a revised diagnosis of mucinous carcinoma with features consistent with PMP. The patient subsequently underwent complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC). She has remained disease-free for 12 months post-operatively.

This case illustrates the crucial role of pathological assessment in guiding treatment for PMP and demonstrates favorable long-term outcomes with aggressive CRS and HIPEC in appropriately selected patients.