# Accelerated Resolution of Pacemaker Pocket Hematoma With Adjunctive Phototherapy: A Case Report

**Authors:** James R Kneller

PMC · DOI: 10.7759/cureus.85378 · 2025-06-04

## TL;DR

This case report shows that using specific phototherapy patches significantly sped up healing of a pacemaker pocket hematoma.

## Contribution

The study demonstrates a sixfold acceleration in hematoma resolution using adjunctive phototherapy devices.

## Key findings

- Complete hematoma resolution occurred in six days, exceeding expert estimates by over 500%.
- Combining X39®, Carnosine®, and Glutathione® devices synergistically accelerated healing.
- The therapy was drug-free and used natural substances with unique biological activities.

## Abstract

Pocket hematoma remains a common complication of pacemaker procedures, causing patient discomfort and functional limitation while predisposing to device infection. A cutaneous phototherapy device known as X39® (LifeWave Inc., Draper, Utah, United States) activates endogenous stem cells through the elevation of glycyl-L-histidyl-L-lysine (GHK) and is found to increase healing rate by 50% following pacemaker extraction. The Carnosine® device (LifeWave Inc., Draper, Utah, United States) activates carnosine dipeptides throughout the body, which act as a high-energy phosphate system that enhances muscle function. The Glutathione® device (LifeWave Inc., Draper, Utah, United States) dramatically boosts levels of glutathione, which supports tissue development and renewal. These skin patches contain natural substances that reflect rays of infrared light from the body's biofield, each having unique biological activity. The present study explores whether the combination of X39®, Carnosine®, and Glutathione® devices may further accelerate wound healing.

A case of pacemaker pocket hematoma complicating the treatment of pneumothorax following a challenging pacemaker implantation procedure was presented in this report. In addition to standard care, devices were placed around the wound and replaced daily. Complete hematoma resolution was achieved after six days, which was >500% faster than expert consensus estimates. In conclusion, amplification of stem cells, carnosine, and glutathione activity appeared to perform synergistically, as healing occurred sixfold faster with this adjunctive therapy. This drug-free technology may be used to accelerate healing following surgical procedures.

## Linked entities

- **Chemicals:** glutathione (PubChem CID 124886)
- **Diseases:** pneumothorax (MONDO:0002076)

## Full-text entities

- **Diseases:** pneumothorax (MESH:D011030), infection (MESH:D007239), Pocket Hematoma (MESH:D006406)
- **Chemicals:** phosphate (MESH:D010710), Glutathione (MESH:D005978), X39 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12229225/full.md

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Source: https://tomesphere.com/paper/PMC12229225