# Treatment of Stage III Grade C Periodontitis With Smoking Cessation Care and Periodontal Surgery Including Regenerative Therapy: A Case Report With a Two-Year Follow-Up

**Authors:** Rio Hisanaga-Mokudai, Kouki Yoshikawa, Atsushi Saito

PMC · DOI: 10.7759/cureus.85449 · 2025-06-06

## TL;DR

A 41-year-old man with severe periodontitis improved significantly after a two-year treatment combining smoking cessation and surgical periodontal care.

## Contribution

This case report demonstrates the effectiveness of integrating smoking cessation and regenerative periodontal surgery in treating severe periodontitis.

## Key findings

- The patient achieved smoking cessation and showed periodontal stability over two years.
- Periodontal therapy significantly improved the patient's oral health-related quality of life.
- Regenerative treatments like rhFGF-2 and GTR helped reduce periodontal pockets and improve bone support.

## Abstract

We report a case of generalized chronic periodontitis requiring periodontal treatment, including smoking cessation care and surgical procedures. With a chief complaint of swelling and pain in the gingiva around #47, a 41-year-old man visited the Tokyo Dental College Suidobashi Hospital. The patient had been smoking cigarettes for 31 years. The initial periodontal examination identified a probing depth (PD) of ≥4 mm in 72.6% of sites and bleeding on probing (BOP) in 45.2% of sites. Radiographic examination demonstrated bone resorption extending to the root apex in #37 and 47, angular bone resorption in #17 and 24, furcation radiolucency in #17, 27, 37, and 47, and horizontal resorption in other areas. Following the clinical diagnosis of stage III grade C periodontitis, non-surgical therapy consisting of smoking cessation care, plaque control, scaling and root planing (SRP), and placement of occlusal splint was performed. Teeth #37 and 47 were extracted due to bone resorption extending to the root apex. The patient had achieved smoking cessation by the end of the non-surgical therapy. Subsequently, surgical periodontal treatment was performed at the selected site. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 was carried out for #14 and 24. Guided tissue regeneration (GTR) was implemented for #17. Open flap debridement was performed in #16, 23, 25, 26, and 27 to facilitate the reduction of periodontal pockets. Following periodontal re-evaluation, supportive periodontal therapy (SPT) was initiated. The patient maintained smoking cessation after the non-surgical therapy, and periodontal stability was observed over a two-year period. Periodontal therapy contributed to a marked improvement in the patient’s oral health-related quality of life.

## Linked entities

- **Diseases:** periodontitis (MONDO:0005076)

## Full-text entities

- **Diseases:** bone resorption (MESH:D001862), chronic periodontitis (MESH:D055113), Periodontitis (MESH:D010518), pain (MESH:D010146), bleeding (MESH:D006470), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12228973/full.md

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Source: https://tomesphere.com/paper/PMC12228973