Vanishing pancreas: CT and MRI features and imaging diagnostic strategies
Yanjin Qin, Danyang Xu, Yuxin Wu, Xiaoqi Zhou, Chenyu Song, Zhi Dong, Lujie Li, Meicheng Chen, Yanji Luo, Huasong Cai, Mimi Tang, Shi-Ting Feng
TL;DR
This paper reviews the CT and MRI features of a vanishing pancreas, caused by conditions like agenesis, fat deposition, and chronic pancreatitis, to improve diagnostic accuracy.
Contribution
The paper provides a comprehensive summary of imaging features and clinical associations for diagnosing a vanishing pancreas.
Findings
Imaging reveals a hypodense pancreas resembling fat or only the pancreatic head and proximal body visible.
Intra-pancreatic fat deposition is linked to genetic and systemic diseases like cystic fibrosis and diabetes.
Dorsal pancreatic agenesis and chronic pancreatitis are key causes of pancreatic atrophy.
Abstract
The vanishing pancreas is a frequently overlooked condition which can result from partial or complete dorsal pancreatic agenesis, intra-pancreatic fat deposition (IPFD) and pancreatic atrophy caused by chronic pancreatitis. A variety of diseases, including cystic fibrosis, maturity-onset diabetes of the young type 8, Shwachman-Diamond syndrome, and Johanson-Blizzard syndrome, can manifest as IPFD. Dorsal pancreatic agenesis can, albeit rarely, coexist with abnormalities or tumors. This review aimed to summarize the various causes that may result in partial or complete vanishing pancreas on computed tomography/magnetic resonance imaging (CT/MRI). We provide a comprehensive review of these imaging findings and their corresponding clinical characteristics, which are crucial for ensuring an accurate diagnosis. By reviewing various causes of pancreatic vanishing, we summarize these imaging…
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Taxonomy
TopicsPancreatic function and diabetes · Congenital Diaphragmatic Hernia Studies · Pancreatic and Hepatic Oncology Research