# Patterns of Acute Gamma‐Hydroxybutyrate Harms Requiring Ambulance Attendance: Should Greater Focus Be on Regional Areas?

**Authors:** Naomi Beard, James Wilson, Bosco C. Rowland, Ziad Nehme, Dan I. Lubman, Rowan P. Ogeil

PMC · DOI: 10.1111/dar.14086 · Drug and Alcohol Review · 2025-05-28

## TL;DR

This study shows that GHB-related ambulance calls have increased in Victoria, especially in regional areas like Greater Geelong, with seasonal patterns observed.

## Contribution

The study highlights the use of ambulance data to track GHB-related harms in regional areas and identifies a growing trend in Greater Geelong.

## Key findings

- There were 16,971 GHB-related ambulance attendances in Victoria from 2015 to 2024.
- GHB-related harms show a seasonal pattern, peaking in the fourth quarter of each year.
- Greater Geelong has seen consistent increases in GHB-related ambulance calls since late 2021.

## Abstract

Gamma‐hydroxybutyrate (GHB) use and attributable harms have been increasing in Europe and Australia. However, there are limited population surveillance tools available to map and track acute GHB‐related harms, particularly outside metropolitan areas. The present study examined GHB‐related ambulance attendances from January 2015 to March 2024 across the state of Victoria, and in Greater Geelong, the region associated with the highest number of attendances outside the state capital.

Retrospective analysis of all GHB‐related ambulance attendances between 1 January 2015 and 31 March 2024 from the Victorian arm of the National Ambulance Surveillance System. Descriptives and time series analyses were used to present demographic and spatio‐temporal patterns.

There were 16,971 ambulance attendances for GHB during the study period. A sinusoidal trend was apparent in the statewide data, suggesting a seasonal factor to GHB‐related attendances, with greater numbers occurring during quarter four of each year. Whilst a seasonal effect was also apparent in Greater Geelong, increases in attendances have been consistent since quarter four of 2021 (between 7% and 34%). The magnitude of these increases was not observed in other regional areas.

Acute GHB‐related harms have increased in Victoria over time, in addition to a seasonal effect being apparent that coincided with summer in the Southern Hemisphere. Our findings support recent media reports from emergency department workers in the region of Greater Geelong that GHB harms have risen. This study demonstrates the value of using ambulance surveillance data to assess pre‐hospital harms resulting from GHB use.

## Linked entities

- **Chemicals:** Gamma-hydroxybutyrate (PubChem CID 10413), GHB (PubChem CID 10413)

## Full-text entities

- **Chemicals:** GHB (MESH:D012978)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12228018/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12228018/full.md

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Source: https://tomesphere.com/paper/PMC12228018