# Rapid Diagnosis of Infective Endocarditis in the Emergency Department: A Case Series Highlighting the Role of Point-of-Care Ultrasound

**Authors:** Jonathan Schonert, Joseph Minardi, Zouyan Lu

PMC · DOI: 10.7759/cureus.87236 · Cureus · 2025-07-03

## TL;DR

This paper presents four emergency cases where point-of-care ultrasound helped quickly diagnose infective endocarditis, improving patient outcomes.

## Contribution

The paper highlights the novel use of POCUS in the ED for rapid identification of infective endocarditis in atypical cases.

## Key findings

- POCUS enabled emergency physicians to detect valvular vegetations in four patients with varied symptoms.
- Early diagnosis via POCUS led to faster antibiotic treatment and specialist involvement.
- Representative images and video clips demonstrated the utility of POCUS for different cardiac valves.

## Abstract

Infective endocarditis can be a challenging and potentially life-threatening diagnosis in the emergency department (ED) due to its often nonspecific presentation. Missed or delayed recognition can result in serious complications. Point-of-care ultrasound (POCUS) is increasingly utilized in emergency medicine to expedite the diagnosis of critical conditions, including endocarditis.

We present a case series of four patients who presented to the ED with varied chief complaints - altered mental status, fever with shortness of breath, delirium, and isolated extremity pain. In each case, emergency physicians identified valvular vegetations using POCUS, prompting expedited consultation and management. Each case involved a different cardiac valve, with representative images and video clips provided. We outline our bedside approach and highlight key sonographic findings to aid in the early identification of infective endocarditis.

Emergency physicians are increasingly equipped to identify life-threatening pathology with bedside imaging. These cases underscore how POCUS can aid in the early diagnosis of infective endocarditis, especially when presentations are atypical. Rapid identification can lead to earlier initiation of antibiotics, targeted diagnostic workups, and specialist involvement, leading to improved patient outcomes.

## Linked entities

- **Diseases:** infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** valvular (MESH:D006349), Infective Endocarditis (MESH:D004696), shortness of breath (MESH:D004417), isolated extremity pain (MESH:D010146), delirium (MESH:D003693), fever (MESH:D005334)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12227156/full.md

## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12227156/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12227156/full.md

---
Source: https://tomesphere.com/paper/PMC12227156