# Trends and collaborations in discoid lupus erythematosus research: a bibliometric analysis from 2010 to 2024

**Authors:** Daichao Zhang, Chaoran Liang, Qiuyue Yin, Yatong Li

PMC · DOI: 10.3389/fmed.2025.1556976 · Frontiers in Medicine · 2025-06-20

## TL;DR

This study uses bibliometric analysis to track research trends and collaborations in discoid lupus erythematosus from 2010 to 2024, highlighting growth and gaps in the field.

## Contribution

The paper provides a novel bibliometric overview of DLE research, identifying trends in collaboration, authorship, and thematic shifts over time.

## Key findings

- Annual publications increased after 2018, but average citations declined.
- The U.S. led in DLE research output and international collaboration.
- Research themes shifted from diagnosis to advanced therapies and immunology.

## Abstract

Discoid lupus erythematosus (DLE) is a chronic autoimmune skin disorder. Research fragmentation in DLE limits cohesive clinical and scientific progress. This bibliometric analysis aimed to clarify publication trends, collaboration networks, and emergent research themes in DLE from 2010 to 2024.

A comprehensive search of the Web of Science Core Collection (WoSCC) used the terms “discoid lupus erythematosus” OR “lupus erythematosus discoid.” English-language articles and reviews (n = 861) were identified and analyzed via the Bibliometrix package in R to examine annual output, authorship, core journals, and keywords evolution.

Annual publications increased notably after 2018, although average citation rates declined. A small group of prolific authors, led by WERTH VP, contributed disproportionately. The United States dominated publication volume and international collaboration, followed by Italy, the United Kingdom, Germany, and China. Keywords analysis showed a shift from initial emphasis on disease classification and diagnosis toward advanced therapies, immunological mechanisms.

Despite growing interest in DLE, it remains underrepresented compared with systemic lupus erythematosus. Broader collaborations, refined diagnostic criteria, and robust clinical trials are essential to enhance therapeutic strategies and patient outcomes in DLE.

## Linked entities

- **Diseases:** discoid lupus erythematosus (MONDO:0019558), systemic lupus erythematosus (MONDO:0007915)

## Full-text entities

- **Diseases:** systemic lupus erythematosus (MESH:D008180), autoimmune skin disorder (MESH:D012871), DLE (MESH:D008179)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12226284/full.md

## References

87 references — full list in the complete paper: https://tomesphere.com/paper/PMC12226284/full.md

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Source: https://tomesphere.com/paper/PMC12226284