# Gastroduodenal Intussusception with Gastric Adenocarcinoma: A Case Report and Review of the Literature

**Authors:** Ryota Omura, Satoshi Ida, Hiroki Tsubakihara, Keisuke Kosumi, Kazuto Harada, Kojiro Eto, Yuji Miyamoto, Masaaki Iwatsuki

PMC · DOI: 10.70352/scrj.cr.25-0184 · Surgical Case Reports · 2025-07-01

## TL;DR

This case report describes a rare instance of gastric cancer causing intussusception in the duodenum and highlights possible treatment options.

## Contribution

The paper presents a rare clinical case of gastric adenocarcinoma with duodenal intussusception and discusses treatment strategies.

## Key findings

- Gastric cancer with duodenal intussusception is often early-stage and well-differentiated.
- Endoscopic reduction and limited surgical resection can be effective treatment options.
- The case highlights the importance of timely diagnosis and management of this rare condition.

## Abstract

Intussusception in adults is a rare condition, and gastric cancer prolapsing into the duodenum is an even rarer phenomenon. We present a case of early gastric cancer originating in the gastric body with duodenal intussusception and discuss the clinical considerations based on the patient’s overall condition and existing literature.

A 69-year-old man with a 30-mm tumor arising from the posterior wall of the gastric body was scheduled for elective surgery. During hospitalization for diabetes mellitus management, he developed sudden epigastric pain and nausea. Upper gastrointestinal endoscopy revealed tumor prolapse into the duodenum, leading to a diagnosis of ball valve syndrome. After successful endoscopic reduction, open local gastrectomy was performed. Pathological examination confirmed a well-differentiated tubular adenocarcinoma, classified as pT1b (SM2) N0M0, pStage IA.

Gastric cancer with duodenal intussusception is often early-stage and characterized by well-differentiated tubular adenocarcinoma. Depending on the patient’s condition, endoscopic resection or limited surgical resection may be viable treatment options for this rare condition.

## Linked entities

- **Diseases:** gastric cancer (MONDO:0001056), diabetes mellitus (MONDO:0005015), adenocarcinoma (MONDO:0004970)

## Full-text entities

- **Diseases:** ball valve syndrome (MESH:D001630), epigastric pain (MESH:D010146), nausea (MESH:D009325), diabetes mellitus (MESH:D003920), Gastroduodenal Intussusception (MESH:D007443), Gastric Adenocarcinoma (MESH:D013274), tumor (MESH:D009369), tubular adenocarcinoma (MESH:D000230), pStage IA (MESH:C536041)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12226140/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12226140/full.md

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Source: https://tomesphere.com/paper/PMC12226140