# When the Esophagus Disrupts the Rhythm: New-Onset Atrial Fibrillation After Stent Placement

**Authors:** Roger Lin, Milan Regmi, Humza Syed, Ahsan Masood

PMC · DOI: 10.7759/cureus.87152 · Cureus · 2025-07-02

## TL;DR

A rare case shows that placing an esophageal stent can lead to new-onset heart rhythm issues, highlighting the need for more awareness and study.

## Contribution

This case report highlights new-onset atrial fibrillation as a rare but important complication of esophageal stent placement.

## Key findings

- An 88-year-old patient developed new-onset atrial fibrillation after esophageal stent placement.
- The anatomical proximity of the esophagus to the left atrium may cause arrhythmias via mechanical or inflammatory pathways.
- New-onset AF after stenting may be underrecognized and requires further study.

## Abstract

Atrial fibrillation (AF) is a recognized complication following esophagectomy and radiotherapy for esophageal cancer but is rarely reported after esophageal stent placement. The mechanisms are thought to include direct mechanical irritation, vagal stimulation, and local inflammation affecting the posterior left atrium. However, the incidence of AF following esophageal stenting remains undocumented. We report the case of an 88-year-old woman with an ulcerated esophageal mass causing dysphagia and weight loss, who developed new-onset AF with rapid ventricular response following esophageal stent placement. The patient had no prior history of arrhythmia and no reversible metabolic or structural cardiac triggers. Telemetry confirmed AF shortly after the procedure. Rate control was achieved with amiodarone. Given recent gastrointestinal bleeding, anticoagulation was deferred at discharge. Her course was further complicated by a lack of follow-up and readmission four months later with progressive decline. This case highlights a rare but important complication of esophageal stenting. The close anatomical proximity of the esophagus to the left atrium may predispose to arrhythmias via mechanical compression and autonomic or inflammatory pathways. While individual case reports have proposed this link, no studies or registries have quantified its incidence. Our case is unique due to the patient’s advanced age, ulcerated mass, and rapid clinical deterioration post-stent. New-onset AF following esophageal stent placement may be underrecognized. Awareness of this potential complication is essential, particularly in patients with limited options for anticoagulation. Future studies should investigate the incidence of AF post-stenting and assess whether targeted monitoring or prophylactic measures are warranted in high-risk populations.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), esophageal cancer (MONDO:0007576)

## Full-text entities

- **Diseases:** AF (MESH:D001281), weight loss (MESH:D015431), Esophagus (MESH:D004938), esophageal mass (MESH:C536030), dysphagia (MESH:D003680), gastrointestinal bleeding (MESH:D006471), inflammation (MESH:D007249), arrhythmia (MESH:D001145)
- **Chemicals:** amiodarone (MESH:D000638)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12225967/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12225967/full.md

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Source: https://tomesphere.com/paper/PMC12225967