# Myofibromas of the jawbones in pediatric patients. A clinicopathological study

## TL;DR

This study examines myofibromas in children's jawbones, focusing on diagnosis and treatment outcomes.

## Contribution

The paper presents a detailed clinicopathological analysis of myofibromas in pediatric jawbone cases.

## Key findings

- Myofibromas predominantly occurred in the mandible and were composed of spindle and stellate cells.
- Complete excision was the treatment for all cases, with only one recurrence reported.
- Smooth muscle actin positivity was observed in most cases.

## Abstract

Myofibromas are infrequent neoplasms that rarely occur in the jawbones. The aim of this study is to present a series of cases of these tumors affecting the jawbones in pediatric patients, as well as to describe their diagnostic methodology and therapeutic approach.

retrospective study of a series of myofibromas of the jawbones diagnosed and treated in a single medical institution in Mexico City from 2002-2022.

There were 14 cases with a median age of 6.5 years (IQR:1-12). Mandible was affected in 8 cases (57.1%), maxilla in 5 (35.8%) and only one case (7.1%) occurred in both jaws. Microscopically, the lesions were composed predominantly by spindle cells, as well as stellate and sometimes pleomorphic in shape, most of which were positive for smooth muscle actin. All cases were treated with complete excision of the lesion and only one presented recurrence.

Once the diagnosis is confirmed and other spindle cell neoplasms have been excluded, resection with free margins represents the treatment of choice.

Key words:Myofibromatosis infantile, myofibroma, myofibroblast, jaw, maxilla, pediatrics.