# Optimization of Collagen Scaffold with Cultured Autologous Chondrocytes for Osteochondritis Dissecans of the Knee: A Case Report

## TL;DR

A 38-year-old man with knee osteochondritis dissecans achieved full recovery after treatment with a collagen scaffold and cultured chondrocytes.

## Contribution

This case report demonstrates successful MACI treatment for adult knee osteochondritis dissecans with rapid recovery.

## Key findings

- The patient showed rapid improvement in pain and functionality 2 months after surgery.
- Full recovery was achieved within 6 months, confirmed by MRI and the mCKRS evaluation.

## Abstract

The treatment of osteochondritis dissecans of the knee has always been a challenge for orthopedic surgeons. We present a case report of a 38-year-old male with severe right knee pain after suffering from an indirect trauma and axial rotation of the knee, limiting knee functionality and impeding his ability to walk, with a diagnosis of osteochondritis dissecans in the trochlea of the knee, who underwent arthroscopic treatment with matrix-induced autologous chondrocyte implantation (MACI). After the surgery, a physical therapy protocol for MACI was implemented, and magnetic resonance images with cartilage mapping were used to evaluate the recovery of the lesion. A total recovery was observed and evaluated with the modified Cincinnati knee rating system (mCKRS). A discussion is provided with evidence and general recommendations for the use of MACI in the treatment of adult OCD of the knee as a possible alternative to conventional treatments. Our case shows a rapid improvement in pain and functionality 2 months after surgery that progressed to full recovery within 6 months.