# Surgical Treatment of Lung Cancer in Situs Inversus Totalis—A Case Report

**Authors:** Janusz Wójcik, Tomasz Grodzki, Jarosław Pieróg, Norbert Wójcik, Dawid Kordykiewicz, Kajetan Kiełbowski, Maja Morozik, Stanisław Brożyna, Paulina Borowik, Małgorzata Edyta Wojtyś

PMC · DOI: 10.3390/reports6040046 · Reports · 2023-09-26

## TL;DR

This case report details the surgical treatment of lung cancer in a patient with a rare condition called situs inversus totalis, where internal organs are mirrored.

## Contribution

The paper adds a new case to the limited literature on surgical management of lung cancer in patients with situs inversus totalis.

## Key findings

- A 56-year-old male with situs inversus totalis underwent successful segmentectomy for non-small-cell lung cancer.
- A review of 21 articles revealed limited data on surgical treatment of lung cancer in patients with situs inversus totalis.
- The case highlights the importance of careful preoperative planning in such rare anatomical conditions.

## Abstract

Situs inversus totalis (SIT) is a congenital anomaly that involves the mirror rearrangement of the thoracic and abdominal internal organs. In this paper, we report a 56-year-old male patient with previously confirmed SIT, who was admitted to the hospital for the diagnosis and surgical treatment of non-small-cell lung cancer, located in the sixth right pulmonary segment. The patient underwent segmentectomy with mediastinal and hilar lymphadenectomy. Furthermore, we screened the PubMed and Embase databases for reports of the surgical treatment of patients with SIT and lung cancer. Articles describing inoperable and disseminated disease, as well as patients qualified for palliative treatment, were not included. Ultimately, we compared 21 articles (including the one described here). Data about the clinical condition, tumor characteristics, treatment, and histopathological examination were extracted and summarized.

## Linked entities

- **Diseases:** non-small-cell lung cancer (MONDO:0005233), situs inversus totalis (MONDO:0010029)

## Full-text entities

- **Diseases:** non-small-cell lung cancer (MESH:D002289), SIT (MESH:D012857), Lung Cancer (MESH:D008175), congenital anomaly (MESH:D000013), tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12225242/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12225242/full.md

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Source: https://tomesphere.com/paper/PMC12225242