# Optimizing oral antibiotic prescribing at hospital discharge: a single center, quasi-experiment pilot study

**Authors:** Ahmad Aloufi, Calvin Ka-Fung Lo, Colin Lee, Adrianna Gunton, Victor Leung

PMC · DOI: 10.1017/ash.2025.10061 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-06-30

## TL;DR

A pilot study found that real-time feedback improved the appropriateness of antibiotic prescriptions at hospital discharge.

## Contribution

The study introduces real-time audit/feedback as a novel method to improve antibiotic prescribing at discharge.

## Key findings

- Appropriateness of antibiotic prescriptions improved from 50% to 83%.
- Median antibiotic duration decreased after the intervention.

## Abstract

Our quasi-experimental pilot study between July to September 2024 showed that real-time audit/feedback for antibiotic discharge prescriptions improved appropriateness from 50% to 83%, while decreasing median antibiotic duration compared to preintervention period. Hospital discharges are an important transition point for antimicrobial stewardship interventions at discharge.

## Full-text entities

- **Diseases:** AMS (MESH:C535557), CAP (MESH:D003147), UTI (MESH:D014552), cystitis (MESH:D003556), bacteremia (MESH:D016470), SSTI (MESH:D018461), Associated pneumonia (MESH:D011014), respiratory infections (MESH:D012141), pyelonephritis (MESH:D011704), CTU (MESH:D000075902), infection (MESH:D007239), Infectious Diseases (MESH:D003141), ID (MESH:C537985), bacteriuria (MESH:D001437), Chronic Obstructive Pulmonary Disease (MESH:D029424), Skin and (MESH:D012871)
- **Chemicals:** cefuroxime (MESH:D002444), amoxicillin-clavulanate (MESH:D019980), cephalexin (MESH:D002506), PO (MESH:D011059)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12224137/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12224137/full.md

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Source: https://tomesphere.com/paper/PMC12224137