# Tr14 gel for the treatment of acute ankle sprains: a plain language summary of the TRAUMED trial

## TL;DR

A new gel called Tr14 was found to be effective for treating acute ankle sprains, providing pain relief as well as a common painkiller.

## Contribution

Tr14 gel demonstrated faster pain relief and improved function for ankle sprains compared to placebo and was as effective as diclofenac.

## Key findings

- Tr14 gel reduced pain from acute ankle sprains better than placebo.
- Tr14 provided faster pain relief and improved ankle function compared to placebo.
- Tr14 was as effective as diclofenac in treating ankle sprain pain.

## Abstract

This is a summary of an article discussing the results of the TRAUMED trial, which was originally published in the Journal of Clinical Medicine. This trial studied how well Tr14 gel helped with ankle sprains compared with either a dummy treatment (placebo) or a common painkiller called diclofenac.

The results of this trial showed that Tr14 was effective at reducing pain caused by an acute or sudden ankle sprain compared with placebo and worked just as well as diclofenac. The results also suggested that Tr14 led to faster pain relief and improved foot and ankle function compared with placebo and was at least as effective as diclofenac.

Clinical Trial Registration:
NCT06192420