# Analysis of risk factors associated with Lymph Node Metastasis and Recurrence Post Thyroid Carcinoma Surgery

## TL;DR

This study identifies key risk factors for lymph node metastasis and recurrence after thyroid cancer surgery, which could help improve patient outcomes.

## Contribution

The study identifies specific independent risk factors for lymph node metastasis and recurrence in thyroid carcinoma patients post-surgery.

## Key findings

- 27% of patients experienced lymph node metastasis or recurrence after thyroid carcinoma surgery.
- Univariate analysis identified nine factors influencing metastasis and recurrence (P<0.05).
- Logistic regression confirmed five independent risk factors: gender, age, hyperthyroidism history, tumor classification/stage, and lesion laterality.

## Abstract

To investigate the risk factors associated with postoperative lymph node metastasis and recurrence in patients with thyroid carcinoma.

Retrospective analysis of clinical data of one hundred patients with thyroid carcinoma who underwent first surgery at the Yellow River Sanmenxia Hospital from June 2019 to July 2023. Record postoperative lymph node metastasis, recurrence, and disease-free survival time. Kaplan Meier survival analysis was used to evaluate the recurrence free survival rate after surgery. Compared the differences between groups with and without lymph node metastasis. Analysis of risk factors for postoperative lymph node metastasis and recurrence in patients with thyroid carcinoma.

In study, 27 out of 100 patients experienced lymph node metastasis and recurrence, with an overall recurrence rate of 27.00%. There were nine cases of intrathyroid recurrence, 15 cases of cervical lymph node metastasis, two cases of intrathyroid metastasis with cervical lymph node metastasis, and one case of lung metastasis. Univariate analysis showed that gender, age, history of hyperthyroidism, tumor classification and staging, tumor diameter, number of cancer foci, unilateral or bilateral lesions, 131I treatment, and surgical methods were influencing factors for postoperative lymph node metastasis and recurrence (P<0.05). Logistic regression analysis identified gender, age, history of hyperthyroidism, tumor classification and stage, unilateral or bilateral disease involvement as independent risk factors for postoperative lymph node metastasis and recurrence in thyroid carcinoma (P<0.05).

Gender, age, history of hyperthyroidism, tumor classification, tumor staging, and unilateral or bilateral lesions are independent risk factors for postoperative lymph node metastasis and recurrence in thyroid carcinoma.