# Scientometric analysis of lipid metabolism in macrophage polarization: 2013-2023

**Authors:** Chenxiao Ye, Xiaosong Ru, Yong Guo

PMC · DOI: 10.3389/fonc.2025.1532862 · Frontiers in Oncology · 2025-06-19

## TL;DR

This paper analyzes global research trends on lipid metabolism in macrophage polarization from 2013 to 2023, highlighting key areas and countries involved.

## Contribution

The study provides a scientometric analysis of lipid metabolism in macrophage polarization, identifying emerging research trends and hotspots.

## Key findings

- 472 publications on lipid metabolism in macrophage polarization were analyzed from 2013 to 2023.
- China produced the highest number of publications in this field.
- Emerging keywords include 'immunometabolism', 'foam cell formation', and 'pathway'.

## Abstract

Macrophage polarization plays a crucial role in the development of various diseases. Simultaneously, macrophage polarization is intimately related to lipid metabolism. To assess the emerging trend of lipid metabolism during macrophage polarization, the present study was carried out.

First, 472 publications that explored lipid metabolism during macrophage polarization were gathered using the Web of Science Core Collection database (WoSCC). The emerging trends were then described using CiteSpace.

Between 2013 and 2023, 46 countries/regions involving 268 institutions carried out studies in this field. The largest number of publications was found in China. Additionally, the most recent burst keywords included “immunometabolism”, “foam cell formation”, and “pathway”, which represented the current frontiers of research.

The detailed analysis of publications pertaining to lipid metabolism during macrophage polarization reveals the current research status and identifies its hotspots.

## Full-text entities

- **Chemicals:** lipid (MESH:D008055)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12222308/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12222308/full.md

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Source: https://tomesphere.com/paper/PMC12222308