This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTED: Paucarmayta et al. Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro. Biomedicines 2020, 8, 73
Ana Paucarmayta, Hannah Taitz, Latoya McGlorthan, Yovanni Casablanca, G. Larry Maxwell, Kathleen M. Darcy, Viqar Syed

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsEstrogen and related hormone effects · Chemotherapy-induced organ toxicity mitigation · Endometrial and Cervical Cancer Treatments
The journal retracts the article, “Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro” [1], cited above.
Following publication, concerns were brought to the attention of the publisher regarding image duplication and the overall reliability of several figures presented in this article.
Adhering to our standard procedure, an investigation was conducted by the Editorial Office and Editorial Board, with input from the Uniformed Services University of the Health Sciences, USA. The investigation confirmed duplications between Figure 4A, ERK1/2 panel [1] and Figure 5D, ERK panel published in [2] and between Figure 5C, ABCG1 panel [1] and Figure 3C, p-STAT 3 panel [3], presenting different experimental conditions and originating from a different authorship group. As a result, the Editorial Board has lost confidence in the integrity of the findings and has decided to retract this article [1] as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30, accessed on 12 March 2025).
This retraction was approved by the Editor-in-Chief of the journal Biomedicines.
A.P., H.T., L.M., Y.C., G.L.M., and K.M.D. agreed to the retraction. The remaining author did not provide a comment on this decision.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Paucarmayta A. Taitz H. Mc Glorthan L. Casablanca Y. Maxwell G.L. Darcy K.M. Syed V. RETRACTED: Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro Biomedicines 202087310.3390/biomedicines 804007332244545 PMC 7236602 · doi ↗ · pubmed ↗
- 2Nokin M.-J. Bellier J. Durieux F. Peulen O. Rademaker G. Gabriel M. Monseur C. Charloteaux B. Verbeke L. van Laere S. Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD 1 pathway activation in breast cancer Breast Cancer Res.20192111910.1186/s 13058-018-1095-730674353 PMC 6343302 · doi ↗ · pubmed ↗
- 3Lin S.-Y. Chang H.-H. Lai Y.-H. Lin C.-H. Chen M.-H. Chang G.-C. Tsai M.-F. Chen J.J.W. Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer P Lo S ONE 201510 e 012330510.1371/journal.pone.012330525955608 PMC 4425490 · doi ↗ · pubmed ↗
