Correction: Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression
María Laura Polo, Marina Riggio, María May, María Jimena Rodríguez, María Cecilia Perrone, Melody Stallings-Mann, Diego Kaen, Marlene Frost, Matthew Goetz, Judy Boughey, Claudia Lanari, Derek Radisky, Virginia Novaro
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsPI3K/AKT/mTOR signaling in cancer
This article has been corrected: The authors discovered duplication errors in Figure 4 and Figure 6. Specifically, in Figure 4B top panel, tumor images stained with pS6 and representing WORT and MFP+WORT-treated tumors were found to overlap. The authors have replaced this panel with new images of the pS6 stained samples from the original experiment.
In Figure 6A there was a duplication of S6 WB images due to an incorrectly labeled picture for T47D cells. The authors have corrected this by using one of two additional sets of T47D WBs from the original experiment and replacing all panels for T47D cells. Uncropped images of two sets of T47D WBs from the original experiments have been provided.
In Figure 6D, an inadvertent duplication of IHC images for pS6 in T47D-myrAkt1 tumors treated with RAPA or RAPA+MFP (bottom right images) was present. The immunostaining was repeated using the same paraffin-embedded tissues from the original experiment, and unmodified data has been provided.
The authors have stated that these corrections do not alter the article’s conclusions. They sincerely apologize for any inconvenience caused to the readers.
Original article: Oncotarget. 2015; 6:22081–22097. 22081-22097. https://doi.org/10.18632/oncotarget.4203