# Chronic Eosinophilic Pneumonia With Overlapping Emphysema and Fibrosis: An Atypical Presentation of Recurrent Pulmonary Tuberculosis

**Authors:** Alejandro Cardona, Simón Villa-Pérez, Sofía Cohen-Mejía, Sara Eusse-Ríos, Andrés Felipe Pérez-Quintero, María Angélica Echeverri-Baena

PMC · DOI: 10.7759/cureus.85228 · Cureus · 2025-06-02

## TL;DR

A patient with chronic respiratory symptoms and high eosinophils was misdiagnosed with pneumonia but later found to have recurring tuberculosis.

## Contribution

Highlights the diagnostic challenges of tuberculosis mimicking interstitial lung diseases in endemic regions.

## Key findings

- The patient's condition was initially misdiagnosed as chronic eosinophilic pneumonia.
- Tuberculosis was confirmed only after prolonged microbiological culture.
- The case illustrates the need for a broad differential in diagnosing interstitial lung diseases.

## Abstract

This case report describes an atypical presentation of recurrent pulmonary tuberculosis in a patient with chronic respiratory symptoms and eosinophilia, initially misdiagnosed as chronic eosinophilic pneumonia. Despite suggestive clinical and radiological features, a final diagnosis was only reached after prolonged microbiological culture. The case underscores the diagnostic complexity of interstitial lung diseases and emphasizes the importance of maintaining a broad differential, particularly in tuberculosis-endemic regions.

## Linked entities

- **Diseases:** chronic eosinophilic pneumonia (MONDO:0004806), pulmonary tuberculosis (MONDO:0006052)

## Full-text entities

- **Diseases:** Pulmonary Tuberculosis (MESH:D014397), Overlapping Emphysema (MESH:D004646), symptoms (MESH:D012816), eosinophilia (MESH:D004802), Chronic Eosinophilic Pneumonia (MESH:C535590), Fibrosis (MESH:D005355), chronic (MESH:D002908), interstitial lung diseases (MESH:D017563), tuberculosis (MESH:D014376)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12218852/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12218852/full.md

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Source: https://tomesphere.com/paper/PMC12218852