# Future innovations for the treatment of facial nerve paralysis

**Authors:** Andrea Weinzierl, Erica Piccinni, Sedef Kollarik, Stefania Konstantinidi, Yoan Civet, Yves Perriard, Pietro Giovanoli, Nicole Lindenblatt

PMC · DOI: 10.1016/j.jpra.2025.05.009 · JPRAS Open · 2025-05-29

## TL;DR

This paper reviews recent innovations in treating facial nerve paralysis to improve patients' quality of life and social well-being.

## Contribution

The paper provides a narrative review of biomedical engineering approaches for facial reanimation.

## Key findings

- Facial nerve paralysis has significant physical and psychosocial impacts.
- Recent technological advances offer new treatment possibilities.
- Biomedical engineering approaches are being explored for facial reanimation.

## Abstract

Facial nerve injury and paralysis causes negative physical and psychosocial effects for afflicted patients. Impaired respiration, articulation, oral competence, as well as insufficient protection of the corneas may cause a markedly decreased quality of life and social isolation. The optimal management of underlying pathologies and the resulting symptoms is thus an ongoing topic of clinical and pre-clinical research and the optimal management of facial nerve injury is continuing to evolve. Recent technological advances have opened up exciting possibilities in this complex field, giving hope to treating physicians and afflicted patients alike. The present narrative review summarizes several concepts regarding biomedical engineering and facial reanimation with an overview of the current literature.

## Linked entities

- **Diseases:** facial nerve paralysis (MONDO:0005665)

## Full-text entities

- **Diseases:** Facial nerve injury (MESH:D020220), facial nerve paralysis (MESH:D005158), paralysis (MESH:D010243), Impaired respiration, articulation, (MESH:D001184)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

76 references — full list in the complete paper: https://tomesphere.com/paper/PMC12213301/full.md

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Source: https://tomesphere.com/paper/PMC12213301