# Small Bowel Stricture in a Crohn's Patient: An Unrelated Etiology

**Authors:** Dhiraj K. Peddu, Matthew Kubina, Ankit Mishra, Molly Stone, Winnie Zou, Jiaqi Shi, David C. Kestenbaum, Scott E. Regenbogen, Jeffrey A. Berinstein

PMC · DOI: 10.1155/crgm/6697889 · Case Reports in Gastrointestinal Medicine · 2025-06-24

## TL;DR

A Crohn's patient developed a new bowel stricture unrelated to the disease, caused by ischemia after surgery.

## Contribution

Highlights the importance of considering non-inflammatory causes for bowel strictures in Crohn's patients.

## Key findings

- A new jejunal and ileal stricture occurred after ileocolic resection.
- The stricture was due to ischemia, not Crohn's disease progression.
- Lack of response to anti-inflammatory treatment suggested an alternative diagnosis.

## Abstract

Small bowel strictures are a common complication of Crohn's disease (CD), which can lead to obstruction, perforation, and fistula formation. However, strictures can stem from other etiologies in CD patients, including malignancy, prior surgery, radiation, and ischemia. We present a patient who developed a new long-segment jejunal and ileal stricture within 2 months after ileocolic resection. What was initially treated as worsening CD was ultimately an unrelated ischemic stricture due to suspected superior mesenteric artery thrombosis following ileocolic resection. The contrasting location of the stricture compared to her previous disease, timing of progression, and lack of response to anti-inflammatory treatment prompted a reassessment of the underlying disease process.

## Linked entities

- **Diseases:** Crohn's disease (MONDO:0005011)

## Full-text entities

- **Diseases:** CD (MESH:D003424), fistula (MESH:D005402), malignancy (MESH:D009369), Small Bowel Stricture (MESH:D003251), ischemia (MESH:D007511), artery thrombosis (MESH:D002341), inflammatory (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12213035/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12213035/full.md

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Source: https://tomesphere.com/paper/PMC12213035