# Development and validation of the antecedents affecting coping questionnaire in patients with multiple sclerosis

**Authors:** Ali Dehghani, Abdolkhalegh Keshavarzi, Yasaman Pourfarid

PMC · DOI: 10.1186/s12883-025-04270-w · BMC Neurology · 2025-07-01

## TL;DR

This study created and validated a questionnaire to measure factors influencing coping in multiple sclerosis patients.

## Contribution

The study introduces a new, validated questionnaire for assessing antecedents of coping in multiple sclerosis patients.

## Key findings

- The questionnaire was reduced from 76 to 24 items after validation.
- Five key factors influencing coping were identified: social support, disease awareness, personal attitudes, spiritual beliefs, and economic-environmental factors.
- The questionnaire showed high internal consistency (0.92) and stability (0.95).

## Abstract

Development of a self-report measure of antecedents affecting coping with multiple sclerosis lead to the identification of influential factors in the coping process and the provision of health cares with a focus on providing or modifying these factors. The current study aimed to develop and validate the antecedents affecting coping scale for multiple sclerosis patients.

This methodological study was conducted in two stages. In the first stage, the concept of coping antecedents was explained using qualitative content analysis approach through interview with 11 MS patients, then the initial items were extracted and the questionnaire was developed. In the second stage, reliability and validation of the questionnaire were evaluated including face, content and construct validity. The76 items in primary items pool reduced to 24 items after evaluating validity and reliability.

Factor analyses revealed 5 factors: social support, awareness about disease, personal opinion and attitudes, spiritual - religious beliefs, and economic - environmental factors. Internal consistency and stability of the developed questionnaire as well as respectively confirmed with 0.92 and 0.95.

The 24 items developed questionnaires is valid and reliable for measurement of antecedents affecting coping among multiple sclerosis patients in Iran.

## Linked entities

- **Diseases:** multiple sclerosis (MONDO:0005301)

## Full-text entities

- **Diseases:** MS (MESH:D009103)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12211942/full.md

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Source: https://tomesphere.com/paper/PMC12211942